GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLCA | cis | rs12908161 | 1 | rs56864281 | chr15:85357649 | LOC388152 | chr15:84867600-84898920:- | -0.23 | -4.09 | 5.29E-5 | Schizophrenia |
| BLCA | cis | rs8078723 | 1 | rs56922390 | chr17:38157021 | ZPBP2 | chr17:38024455-38034144:+ | -0.21 | -3.94 | 9.66E-5 | Neutrophil count;White blood cell count;C-reactive protein and white blood cell count |
| BLCA | cis | rs477692 | 1 | rs569235 | chr10:131411620 | MGMT | chr10:131265454-131565783:+ | 0.21 | 4.66 | 4.38E-6 | Response to temozolomide |
| BLCA | cis | rs2243480 | 1 | rs56985706 | chr7:65394562 | CCT6P1 | chr7:65216092-65228661:+ | 0.31 | 4.38 | 1.53E-5 | Diabetic kidney disease |
| BLCA | cis | rs7714584 | 1 | rs57001853 | chr5:150272452 | LOC134466 | chr5:150310000-150326146:- | 0.46 | 5.97 | 5.47E-9 | Crohn's disease |
| BLCA | cis | rs2243480 | 1 | rs57057549 | chr7:65405738 | CCT6P1 | chr7:65216092-65228661:+ | 0.33 | 4.47 | 1.02E-5 | Diabetic kidney disease |
| BLCA | cis | rs2143950 | 1 | rs57075379 | chr14:35577801 | PPP2R3C | chr14:35554679-35591679:- | 0.27 | 4.26 | 2.6E-5 | Atopic dermatitis |
| BLCA | cis | rs9815354 | 1 | rs57479675 | chr3:41798038 | ULK4 | chr3:41288091-42003660:- | 0.62 | 9.52 | 1.95E-19 | Diastolic blood pressure |
| BLCA | cis | rs2076028 | 1 | rs5750621 | chr22:38956166 | JOSD1 | chr22:39081549-39096459:- | -0.23 | -3.95 | 9.43E-5 | Resting heart rate |
| BLCA | cis | rs2076028 | 1 | rs5750622 | chr22:38956464 | JOSD1 | chr22:39081549-39096459:- | -0.23 | -3.86 | 0.000135 | Resting heart rate |
| BLCA | cis | rs2076028 | 1 | rs5750672 | chr22:39104168 | JOSD1 | chr22:39081549-39096459:- | 0.23 | 3.96 | 9.11E-5 | Resting heart rate |
| BLCA | cis | rs5758659 | 1 | rs5751255 | chr22:42648408 | C22orf32 | chr22:42475699-42480287:+ | 0.2 | 5.32 | 1.74E-7 | Cognitive function |
| BLCA | cis | rs5758659 | 1 | rs5751255 | chr22:42648408 | CCDC134 | chr22:42196678-42222303:+ | 0.26 | 4.26 | 2.6E-5 | Cognitive function |
| BLCA | cis | rs5758659 | 1 | rs5751255 | chr22:42648408 | CYP2D6 | chr22:42522502-42526883:- | -0.36 | -7.61 | 2.12E-13 | Cognitive function |
| BLCA | cis | rs5758659 | 1 | rs5751255 | chr22:42648408 | NAGA | chr22:42454339-42466846:- | 0.3 | 5.39 | 1.25E-7 | Cognitive function |